Over the past few years, hydrophobically modified inulin (HMI) has gained considerable attention due to its multitudinous features. The targeted release of drugs remains a subject of research interest. Moreover, it is important to explore the properties of short-chain fatty acids (SCFAs) inulin esters because they are less studied. Additionally, HMI has been used to stabilize various dispersion formulations, which have been observed to be safe because inulin is generally recognized as safe (GRAS). However, the results regarding HMI-based dispersion products are dispersed throughout the literature. This comprehensive review is discussed the possible limitations regarding SCFAs inulin esters, real food dispersion formulations, and HMI drugs. The results revealed that SCFAs inulin esters can regulate the human gut microbiota and increase the biological half-life of SCFAs in the human body. This comprehensive review discusses the versatility of HMI as a promising excipient for the production of hydrophobic drugs.

在过去的几年中，疏水修饰的菊粉（HMI）由于其众多的特性而受到了广泛的关注。药物的靶向释放仍然是研究的主题。此外，重要的是探索短链脂肪酸（SCFA）菊粉酯的性质，因为对它们的研究较少。此外，HMI已用于稳定各种分散体配方，由于菊粉通常被认为是安全的（GRAS），因此已被认为是安全的。但是，有关基于HMI的分散产品的结果分散在整个文献中。这篇全面的综述讨论了有关SCFA菊粉酯，真正的食品分散制剂和HMI药物的可能限制。结果表明，SCFAs菊粉酯可以调节人体肠道菌群并增加SCFAs在人体中的生物半衰期。这篇全面的综述讨论了HMI作为疏水性药物生产的有希望的赋形剂的多功能性。