While evidence suggests a strong association between alcohol and hypertension, little is known about the profile of patients with alcohol dependence comorbid with hypertension. This study aimed to clarify the clinical characteristics and health problems of this population through a web-based questionnaire survey using a research company's panel of adults in Japan. Of 20 000 regular drinkers, 176 on treatment for hypertension and with alcohol dependence (confirmed and/or an Alcohol Use Disorders Identification Test score ≥15 points) were included. Participants were asked about their health-related quality of life, work productivity, blood pressure (BP) control, receipt of brief interventions, and awareness of their alcohol dependence. Results were compared between the BP-controlled and BP-uncontrolled groups. The mean EQ-5D utility score was 0.838 in the entire population, and 0.786 vs. 0.892 in the groups (p < 0.0001). When 133 ‘employed’ participants were compared, productivity loss was more apparent in the BP-uncontrolled group (presenteeism, 27.3% vs. 6.1%, p < 0.0001; absenteeism, 10.7% vs. 1.0%, p = 0.0003). The rate of dissatisfaction with BP control was 55.1% in the entire population (most [76.3%] of those dissatisfied considered alcohol a cause of inadequate BP control), ~78% in the uncontrolled group, and ~34% in the controlled group. Of those previously advised to reduce drinking or abstain from alcohol (60.2% of all participants), 63% (BP-uncontrolled group) and 55% (BP-controlled group) decreased their drinking. Though more than twice as many participants thought themselves to be alcohol-dependent in the BP-uncontrolled group than in the controlled group (41% vs. 15%), most (59% vs. 85%) showed no self-awareness of alcohol dependence. Patients with alcohol dependence comorbid with hypertension had impaired health status and reduced work productivity. They thought alcohol was the most common cause of inadequate BP control. Treatment beyond brief interventions is needed to enhance their awareness of alcohol dependence and their motivation to reduce drinking.

虽然有证据表明酒精和高血压之间有很强的关联，但对酒精依赖患者合并高血压的情况知之甚少。本研究旨在通过使用日本一家研究公司的成人小组进行的基于网络的问卷调查来阐明该人群的临床特征和健康问题。在 20 000 名经常饮酒者中，包括 176 名接受高血压治疗和酒精依赖（确诊和/或酒精使用障碍识别测试得分≥15 分）的人。参与者被问及与健康相关的生活质量、工作效率、血压 (BP) 控制、接受简短干预措施以及对酒精依赖的认识。结果在血压控制组和血压未控制组之间进行比较。平均 EQ-5D 效用得分为 0。p  < 0.0001)。当比较 133 名“受雇”参与者时，BP 未控制组的生产力损失更为明显（出勤率，27.3% 对 6.1%，p  < 0.0001；缺勤，10.7% 对 1.0%，p = 0.0003）。整个人群对血压控制的不满意率为 55.1%（大多数不满意的人 [76.3%] 认为酒精是血压控制不足的原因），未控制组约为 78%，对照组约为 34%。在之前建议减少饮酒或戒酒的人中（占所有参与者的 60.2%），63%（血压未控制组）和 55%（血压控制组）减少了饮酒量。尽管血压不受控制组中认为自己依赖酒精的人数是对照组的两倍多（41% 对 15%），但大多数（59% 对 85%）没有表现出对酒精的自我意识依赖性。伴有高血压的酒精依赖患者的健康状况受损，工作效率降低。他们认为酒精是导致血压控制不足的最常见原因。