Malaria and tuberculosis are no longer considered to be neglected diseases by the World Health Organization. However, both are huge challenges and public health problems in the world, which affect poor people, today referred to as neglected populations. In addition, malaria and tuberculosis present the same difficulties regarding the treatment, such as toxicity and the microbial resistance. The increase of Plasmodium resistance to the available drugs along with the insurgence of multidrug- and particularly tuberculosis drug-resistant strains are enough to justify efforts towards the development of novel medicines for both diseases. This literature review provides an overview of the state of the art of antimalarial and antituberculosis chemotherapies, emphasising novel drugs introduced in the pharmaceutical market and the advances in research of new candidates for these diseases, and including some aspects of their mechanism/sites of action.

中文翻译：

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疟疾和肺结核作为被忽视人群的疾病：化学疗法的最新发展和新药的寻找进展

世界卫生组织不再将疟疾和结核病视为被忽视的疾病。但是，这两者都是世界范围内的巨大挑战和公共卫生问题，它们影响到今天被称为被忽视人口的穷人。此外，疟疾和结核病在治疗方面也存在同样的困难，例如毒性和微生物耐药性。对可用药物的疟原虫抗药性的增加，以及对多种药物，特别是结核病抗药性菌株的大量涌现，足以证明为开发针对这两种疾病的新药而进行的努力是合理的。这篇文献综述概述了抗疟和抗结核化学疗法的最新发展，