MICA polymorphisms associated with antithyroid drug‐induced agranulocytosis in the Chinese Han population,Immunity, Inflammation and Disease

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MICA polymorphisms associated with antithyroid drug‐induced agranulocytosis in the Chinese Han population
Immunity, Inflammation and Disease ( IF 2.493 ) Pub Date : 2020-10-05 , DOI: 10.1002/iid3.359
Xiaojuan Gong _{1,

2} , Pu Chen ₁ , Pan Ma ₂ , Jiayang Gao ₂ , Jingsi Yang ₂ , Hui Guo ₁ , Chunxia Yan ₂ , Bao Zhang ₂ , Yayi He ₁

Affiliation

Graves' disease (GD) is a clinical autoimmune thyroid disease. During the treatment of GD, antithyroid drug‐induced agranulocytosis (TIA) is a common and even life‐threatening adverse drug reaction. Previous studies suggested that susceptibility to TIA is strongly associated with HLA‐B*27:05, HLA‐B*38:02, and HLA‐DRB1*08:03 genetic variation and six single nucleotide polymorphisms (SNPs) in MICA genes.

更新日期：2020-11-12

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