Human adenoviruses (HAdVs) are responsible for various clinical diseases. Molecular epidemiological studies of respiratory HAdVs are limited in Turkey. To determine the main genotypes and epidemiological characteristics of HAdVs in patients with respiratory symptoms. HAdV PCR‐positive extracts of nasal/nasopharyngeal specimens sent to the Turkish Public Health Institution from various cities of Turkey in 2015–2016 were investigated by seminested PCR. Partial sequence analysis of the hexon gene of HAdVs was performed. SPSSv.24.0 was used. A total of 23/68 (33.82%) HAdV‐positive samples were amplified. Mastadenovirus B, C, D, and F were detected and mastadenovirus B (10/23; 43.5%) and C (10/23; 43.5%) were predominant strains. Interestingly, HAdV‐F known to have gastrointestinal system tropism was detected in two patients with respiratory symptoms. HAdV‐B3 was the most prevalent genotype (9/23; 39.1%). Also, HAdV‐B7 is defined as a reemerging pathogen. It is noteworthy that there is a cluster of four HAdV‐C strains showing a close paraphyletic relationship with HAdV‐2/6 intertypic recombination. To our knowledge, this is the first study showing that HAdV‐B7 reemerging pathogen circulating in patients with respiratory infections in our country. It is also necessary to emphasize that HAdV‐2/6 recombinant strains were detected in this study for the first time in Turkey.

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与土耳其呼吸道感染有关的人类腺病毒的分子特征

人腺病毒（HAdV）负责各种临床疾病。在土耳其，呼吸道HAdV的分子流行病学研究非常有限。确定具有呼吸道症状的患者HAdV的主要基因型和流行病学特征。使用半巢式PCR对2015-2016年从土耳其各城市送往土耳其公共卫生机构的鼻/鼻咽标本的HAdV PCR阳性提取物进行了调查。对HAdV的六邻体基因进行了部分序列分析。使用了SPSSv.24.0。总共扩增了23/68（33.82％）HAdV阳性样品。检测到乳腺腺病毒B，C，D和F，而乳腺腺病毒B（10/23; 43.5％）和C（10/23; 43.5％）是主要菌株。有趣的是，在两名有呼吸道症状的患者中检测到已知具有胃肠道嗜性的HAdV-F。HAdV-B3是最流行的基因型（9/23； 39.1％）。同样，HAdV-B7被定义为重新出现的病原体。值得注意的是，有一簇四个HAdV-C菌株显示与HAdV-2 / 6型间重组具有密切的亲缘关系。据我们所知，这是第一项研究表明，HAdV-B7能使我国呼吸道感染患者的病原体重新出现。还需要强调的是，这项研究中首次在土耳其检测到HAdV-2 / 6重组菌株。这是第一项研究表明，HAdV-B7在我国呼吸道感染患者中会重新产生病原体。还需要强调的是，这项研究中首次在土耳其检测到HAdV-2 / 6重组菌株。这是第一项研究表明，HAdV-B7在我国呼吸道感染患者中会重新产生病原体。还需要强调的是，这项研究中首次在土耳其检测到HAdV-2 / 6重组菌株。