The third E. coli and the Mucosal Immune System (ECMIS) meeting was held at Ghent University in Belgium from 2 to 5 June 2019. It brought together an international group of scientists interested in mechanisms of colonization, host response, and vaccine development. ECMIS distinguishes itself from related meetings on these enteropathogens by providing a greater emphasis on animal health and disease and covering a broad range of pathotypes, including enterohemorrhagic, enteropathogenic, enterotoxigenic, enteroaggregative, and extraintestinal pathogenic Escherichia coli. As it is well established that the genus Shigella represents a subspecies of E. coli, these organisms along with related enteroinvasive E. coli are also included. In addition, Tannerella forsythia, a periodontal pathogen, was presented as an example of a pathogen which uses its surface glycans for mucosal interaction. This review summarizes several highlights from the 2019 meeting and major advances to our understanding of the biology of these pathogens and their impact on the host.

中文翻译：

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大肠杆菌与宿主环境的有趣相互作用和干扰定植的创新策略：2019 年大肠杆菌和粘膜免疫系统会议总结

第三届大肠杆菌和粘膜免疫系统 (ECMIS) 会议于 2019 年 6 月 2 日至 5 日在比利时根特大学举行。会议汇集了对定植机制、宿主反应和疫苗开发感兴趣的国际科学家小组。ECMIS 通过更加强调动物健康和疾病并涵盖广泛的致病型，包括肠出血性、肠致病性、肠毒性、肠聚集性和肠外致病性大肠杆菌，将自己与有关这些肠道病原体的相关会议区分开来。众所周知，志贺氏菌属代表大肠杆菌的一个亚种，这些微生物连同相关的肠侵入性大肠杆菌也包括在内。此外，牙周病原菌Tannerella forsythia被作为利用其表面聚糖进行黏膜相互作用的病原菌的一个例子。这篇综述总结了 2019 年会议的几个亮点，以及我们对这些病原体生物学及其对宿主影响的理解的重大进展。