Abstract Cryptosporidiosis is the second major cause of diarrheal illness in humans and animals. Despite being a major cause of digestive anomalies in goats of Khyber Pakhtunkhwa (Pakistan), there is a serious dearth of data regarding the infection induced alterations in physiological biomarkers. The present study was conducted to record changes in vital body parameters caused by the cryptosporidiosis. A total of 384 fecal and blood samples were randomly collected from adult goats showing clinical signs of the disease. Fecal samples were examined using the modified Ziehl Neelsen acid fast staining, and were confirmed for the infection using two-step nested PCR assay. A total of 66 animals were included in the diseased group, while 57 were included in healthy animals group. Blood samples were processed for measurement of hematological and biochemical parameters using automatic analyzer. Diseased goats showed significant increase in lymphocytes, eosinophils and packed cell volume (P

中文翻译：

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隐孢子虫感染山羊宿主生物标志物的变化

摘要 隐孢子虫病是人类和动物腹泻病的第二大病因。尽管是开伯尔-普赫图赫瓦（巴基斯坦）山羊消化异常的主要原因，但严重缺乏有关感染引起的生理生物标志物改变的数据。本研究旨在记录由隐孢子虫病引起的重要身体参数的变化。从表现出该疾病临床症状的成年山羊中随机收集了 384 份粪便和血液样本。使用改良的 Ziehl Neelsen 抗酸染色检查粪便样本，并使用两步巢式 PCR 测定确认感染。患病组共66只动物，健康动物组共57只。使用自动分析仪处理血液样本以测量血液学和生化参数。患病山羊的淋巴细胞、嗜酸性粒细胞和堆积细胞体积显着增加（P