Purpose

To investigate the incidence and peak elevation of conjunctival prolapse during short-term open eye scleral lens wear and its association with lens fitting characteristics.

Methods

Ten young, healthy adults (mean age ± SD, 30 ± 4 years) wore a high Dk sealed scleral lens for 90 min with an initial central post-lens fluid reservoir thickness defined as low (144 ± 23 μm), medium (487 ± 63 μm), and high (726 ± 55 μm). Optical coherence tomography was used to quantify limbal clearance, lens settling, and changes in conjunctival thickness.

Results

The incidence of conjunctival prolapse was 37% across all fluid reservoir thickness conditions, with 80% of participants exhibiting conjunctival prolapse at least once. Prolapse was observed more frequently nasally (73%) than temporally (27%) (p < 0.01). The peak prolapse elevation did not vary with fluid reservoir thickness condition or anatomical location (both p > 0.05). For the low fluid reservoir thickness condition, eyes with conjunctival prolapse had greater initial limbal clearance (97 ± 38 μm compared to 43 ± 34 μm, p = 0.01) and more settling after 90 min of lens wear (−85 ± 30 μm compared to −34 ± 29 μm, p < 0.01). Greater limbal settling was associated with a higher peak elevation of the conjunctival prolapse (r = 0.48, p = 0.02), but not with landing zone tissue compression (r = 0.22, p = 0.33) or the initial or final limbal fluid reservoir thickness asymmetry (r ≤ 0.07, p > 0.05).

Conclusion

Conjunctival prolapse was commonly observed during short-term sealed scleral lens wear in healthy eyes. The peak elevation of the conjunctival prolapse was associated with the extent of limbal settling, but not landing zone tissue compression or fluid reservoir thickness asymmetry.

中文翻译：

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戴睁眼巩膜镜时结膜脱垂

目的

研究短期睁眼巩膜镜片佩戴期间结膜脱垂的发生率和峰值升高及其与镜片配戴特性的关系。

方法

10 名年轻、健康的成年人（平均年龄 ± SD，30 ± 4 岁）佩戴高 Dk 密封巩膜镜片 90 分钟，初始中央镜片后积液厚度定义为低 (144 ± 23 μm)、中 (487 ± 63 μm) 和高 (726 ± 55 μm)。光学相干断层扫描用于量化角膜缘间隙、晶状体沉降和结膜厚度变化。

结果

在所有储液层厚度条件下，结膜脱垂的发生率为 37%，80% 的参与者至少表现出一次结膜脱垂。鼻部 (73%) 比颞部 (27%) 更频繁地观察到脱垂 ( p < 0.01)。峰值脱垂高度不随流体储层厚度条件或解剖位置而变化（均p > 0.05）。对于低流体储层厚度条件，结膜脱垂的眼睛具有更大的初始角膜缘间隙（97 ± 38 μm 与 43 ± 34 μm 相比，p = 0.01）并且在佩戴镜片 90 分钟后更稳定（-85 ± 30 μm 与−34 ± 29 μm，p < 0.01)。较大的角膜缘沉降与较高的结膜脱垂峰值相关。r = 0.48, p = 0.02)，但与着陆区组织压缩 ( r = 0.22, p = 0.33) 或初始或最终角膜缘液储层厚度不对称 ( r ≤ 0.07, p > 0.05)无关。

结论

在健康眼睛短期佩戴密封巩膜镜期间，通常会观察到结膜脱垂。结膜脱垂的峰值升高与角膜缘沉降的程度有关，但与着陆区组织压缩或储液层厚度不对称无关。