Abstract

The aerial parts of Ageratina vernalis provided the new germacranolide 1,10-epoxydeltoidin A (3), together with the known pentacyclic triterpenoid hopane-6α,22-diol (1), and the also known germacranolides deltoidin A (2) and 15-hydroxydeltoidin A (4). In addition, pTsOH catalyzed cyclization of 2 afforded the new guaianolide 5. The absolute configuration of 2, 4, and 5 was assigned by vibrational circular dichroism spectroscopy, while the complete ¹H and ¹³C NMR data assignments of 2-5 followed from 1 D- and 2 D-NMR experiments.

中文翻译：

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一种新的 Germacranolide 来自 Ageratina vernalis

摘要

Ageratina vernalis的地上部分提供了新的germacranolides 1,10-epoxydeltoidin A ( 3 )，以及已知的五环三萜类hopane-6 α ,22-diol ( 1 )，以及也已知的germacranolides deltoidin A ( 2 ) 和15 -羟基deltoidin A ( 4 )。此外，p TsOH 催化2的环化得到新的愈创木酚内酯5。2、4和5的绝对构型由振动圆二色光谱指定，而完整的¹ H 和¹³2-5的 C NMR 数据分配来自1 D-和 2 D-NMR 实验。