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Making sense of Mendelian genes
Interdisciplinary Science Reviews ( IF 1.1 ) Pub Date : 2020-07-02 , DOI: 10.1080/03080188.2020.1794387
Gregory Radick 1
Affiliation  

ABSTRACT An enduring legacy from the heyday of Mendelian genetics is talk of ‘genes for'. Such talk suggests straightforwardly that genes make characters. But for over a century, thoughtful biologists have insisted such an understanding is mistaken. For them, a gene is a chromosomal difference that, when internal and external environments are otherwise equal, makes a phenotypic difference; ‘genes for’ talk is but shorthand for this more complex understanding. This paper examines the remarkable durability of the disowned, deterministic character-making understanding, placing particular emphasis on the role of the traditional, start-with-Mendel curriculum in investing that understanding with a heuristic power which later teaching may never fully displace. The paper also reports on recent experimental work exploring the potential of a reordered curriculum for teaching genetics without bolstering genetic determinism.

中文翻译:

理解孟德尔基因

摘要 孟德尔遗传学鼎盛时期的一项持久遗产是关于“基因”的讨论。这样的谈话直截了当地表明基因造就了性格。但是一个多世纪以来,有思想的生物学家一直坚持这样的理解是错误的。对他们来说,基因是一种染色体差异,当内部和外部环境相同时,会产生表型差异;'genes for' 谈话只是这种更复杂理解的简写。本文考察了被否认的、确定性的性格塑造理解的显着持久性,特别强调了传统的、从孟德尔开始的课程在用启发式力量投资这种理解方面的作用,后来的教学可能永远不会完全取代这种力量。
更新日期:2020-07-02
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