There is an increasing awareness of the impact of age and sex on cardiovascular diseases (CVDs). Differences in physiology are suspected. Beta‐adrenoceptors (beta‐ARs) are an important drug target in CVD and potential differences might have significant impact on the treatment of many patients. To investigate whether age and sex affects beta‐AR function, we analysed a large data set on beta‐AR‐induced inotropy in human atrial trabeculae.

中文翻译：

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性别和年龄对β-肾上腺素能受体介导的右心房小梁肌力无影响

人们越来越意识到年龄和性别对心血管疾病 (CVD) 的影响。怀疑生理上的差异。β-肾上腺素能受体（β-ARs）是心血管疾病的重要药物靶点，潜在差异可能对许多患者的治疗产生重大影响。为了研究年龄和性别是否会影响 β-AR 功能，我们分析了有关 β-AR 诱导的人心房小梁肌力的大量数据集。