This review explores state-of-the-art and new perspectives description of scaffold-based strategies utilized in in-suit bone tissue engineering. The bone defects caused by severe trauma and tumor resection can't be healed by themselves. It needs to apply exogenous bone induction materials to recover effectively. In recent years, with the rapid development of bone repair materials and tissue engineering, in-situ bone tissue engineering provides a new choice for the treatment of bone defects. The key point is to prepare cell-free scaffolds instead of grafts and implant them in the defect area to achieve bone healing. Therefore, this paper describes in detail the preparation needs, in-situ preparation methods, functional bone repair scaffold and the application of functional scaffold composite in in-situ tissue engineering.

这篇综述探索了在套装骨组织工程中使用的基于支架的策略的最新和新观点描述。严重的创伤和肿瘤切除所导致的骨缺损无法自行治愈。需要使用外源性骨诱导材料来有效地恢复。近年来，随着骨修复材料和组织工程技术的飞速发展，原位骨组织工程技术为骨缺损的治疗提供了新的选择。关键是准备无细胞支架而不是移植物，并将其植入缺损区域以实现骨愈合。因此，本文详细描述了现场的制备需求制备方法，功能性骨修复支架以及功能性支架复合材料在原位组织工程中的应用。