Delirium is a common neurocognitive disorder in hospital settings, characterised by fluctuating impairments in attention and arousal following an acute precipitant. Electroencephalography (EEG) is a useful method to understand delirium pathophysiology. We performed a systematic review to investigate associations between delirium and EEG measures recorded prior, during, and after delirium. A total of 1,655 articles were identified using PsycINFO, Embase and MEDLINE, 31 of which satisfied inclusion criteria. Methodological quality assessment was undertaken, resulting in a mean quality score of 4 out of a maximum of 5. Qualitative synthesis revealed EEG slowing and reduced functional connectivity discriminated between those with and without delirium (i.e. EEG during delirium); the opposite pattern was apparent in children, with cortical hyperexcitability. EEG appears to have utility in differentiating those with and without delirium, but delirium vulnerability and the long-term effects on brain function require further investigation. Findings provide empirical support for the theory that delirium is a disorder of reduced functional brain integration.

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调查脑电图测量如何与谵妄相关：系统评价

谵妄是医院环境中常见的神经认知障碍，其特征是急性沉淀后注意力和觉醒的波动性损害。脑电图 (EEG) 是了解谵妄病理生理学的有用方法。我们进行了系统评价，以调查谵妄与谵妄之前、期间和之后记录的脑电图测量值之间的关联。使用 PsycINFO、Embase 和 MEDLINE 共识别出 1,655 篇文章，其中 31 篇符合纳入标准。进行了方法学质量评估，结果平均质量得分为 4 分（满分为 5 分）。定性综合显示脑电图减慢和功能连接性降低，可区分谵妄和非谵妄（即谵妄期间的脑电图）。相反的模式在儿童中很明显，与皮质过度兴奋。脑电图似乎有助于区分谵妄和非谵妄，但谵妄的易感性和对大脑功能的长期影响需要进一步研究。研究结果为谵妄是一种功能性大脑整合障碍的理论提供了经验支持。