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The Prevalence, Mortality rate and functional outcome of Intracerebral hemorrhage according to age sex and ethnic group in the state of Qatar
Clinical Neurology and Neurosurgery ( IF 1.9 ) Pub Date : 2020-12-01 , DOI: 10.1016/j.clineuro.2020.106255
Maher Saqqur , Abdul Salam , Ali Ayyad , Naveed Akhtar , Musab Ali , Adnan Khan , Yahya Imam , Sujatha Joseph , Salman Al Jerdi , Ashfaq Shuaib

OBJECTIVE To investigate the prevalence of intracerebral hemorrhage (ICH) using stroke database from the main tertiary hospital in Qatar (Hamad General Hospital) over the period of Dec 2013 to Oct 2017. METHODS The prevalence of ICH was calculated based on age groups and ethnicity (Qatari nationals, non-Qatari Arab, South east Indian (SI) and Far East Asians (FE)). Thirty-day case fatality rate, poor clinical outcome at discharge (modified Rankin scale (mRS):3-6) and poor long-term outcome (mRS at 90 days: 3-6) were calculated per each age group sex and ethnicity. RESULT There were 653/4039 (16 %) with ICH. The median age was 53 (IQ range: 45-64) with a male/female ratio: 557/96 (85.3/14.7 %). The 30-day mortality rate was 14.7 % (96/653), poor outcome at discharge (mRS 3-6): 66.8 % (436/653) and poor long-term outcome (mRS 90 days:3-6) 50.1 % (199/397). The prevalence of ICH in Qatar was 24.9 per 100 000. The highest mortality rate was seen in the elderly (≥ 70 years old) (16/67 (23.9 %)) and young group (48/291 (16.5 %)). The most common ethnic group among our ICH population are the following: FE (40.59 per 100 000), Qatari (25.26 per 100 000) and SI ethnic group (24.97 per 100 000). In multiple logistic regression analysis only, old age (≥ 70 years old) was associated with 30 days mortality (adj OR: 2.51, 95 % CI: 1.14-5.54, P = 0.023). Similar regression analysis was also observed that age ≥ 70 years old (adj. OR: 4.18, 95 % CI: 1.27-13.77, P = 0.019), sex (male) (adj. OR: 0.21, 95 % CI: 0.08-0.56, P = 0.002), and ethnicity (SI vs Qatari: adj. OR: 4.08, 95 % CI: 1.28-12.92, P = 0.017); (FE vs Qatari: adj. OR: 2.22, 95 % CI: 0.65-7.67, P = 0.203) are statistically associated with poor outcome. CONCLUSION The prevalence of ICH was high in the elderly and in the FE, Qatari, and SI ethnic group. Further studies are needed to better understand the differences in ICH prognosis in multiethnic groups.

中文翻译:

卡塔尔州不同年龄性别和种族的脑出血患病率、死亡率和功能结果

目的利用卡塔尔主要三级医院(哈马德总医院)2013年12月至2017年10月期间的卒中数据库调查脑出血(ICH)的患病率。方法根据年龄组和种族计算脑出血(ICH)的患病率。卡塔尔国民、非卡塔尔阿拉伯人、东南亚印度人 (SI) 和远东亚洲人 (FE)。根据每个年龄组的性别和种族计算 30 天病死率、出院时较差的临床结果(改良的 Rankin 量表 (mRS):3-6)和较差的长期结果(90 天时的 mRS:3-6)。结果 有 653/4039 (16 %) 患有 ICH。中位年龄为 53 岁(IQ 范围:45-64),男女比例为 557/96(85.3/14.7 %)。30 天死亡率为 14.7 % (96/653),出院时预后不良 (mRS 3-6):66.8 % (436/653) 和长期预后不良 (mRS 90 天:3-6) 50。1% (199/397)。卡塔尔的 ICH 患病率为每 10 万人 24.9 人。死亡率最高的是老年人(≥70 岁)(16/67(23.9%))和年轻人(48/291(16.5%))。我们的 ICH 人口中最常见的族群如下:FE(每 10 万人 40.59 人)、卡塔尔人(每 10 万人 25.26 人)和 SI 族群(每 10 万人 24.97 人)。仅在多元逻辑回归分析中,高龄(≥ 70 岁)与 30 天死亡率相关(调整 OR:2.51,95% CI:1.14-5.54,P = 0.023)。还观察到类似的回归分析,年龄 ≥ 70 岁(调整 OR:4.18,95 % CI:1.27-13.77,P = 0.019),性别(男性)(调整 OR:0.21,95 % CI:0.08-0.56 , P = 0.002) 和种族(SI vs 卡塔尔:调整 OR:4.08,95% CI:1.28-12.92,P = 0.017);(FE vs 卡塔尔:调整或:2.22,95% CI:0.65-7.67,P = 0。203)在统计学上与不良结果相关。结论 ICH 在老年人和 FE、Qatari 和 SI 族群中的患病率很高。需要进一步研究以更好地了解多种族人群 ICH 预后的差异。
更新日期:2020-12-01
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