Chromatin remodeler complexes regulate gene transcription, DNA replication and DNA repair by changing both nucleosome position and post-translational modifications. The chromatin remodeler complexes are categorized into four families: the SWI/SNF, INO80/SWR1, ISWI and CHD family. In this review, we describe the subunits of these chromatin remodeler complexes, in particular, the recently identified members of the ISWI family and novelties of the CHD family. Long non-coding (lnc) RNAs regulate gene expression through different epigenetic mechanisms, including interaction with chromatin remodelers. For example, interaction of lncBRM with BRM inhibits the SWI/SNF complex associated with a differentiated phenotype and favors assembly of a stem cell-related SWI/SNF complex. Today, over 50 lncRNAs have been shown to affect chromatin remodeler complexes and we here discuss the mechanisms involved.

染色质重塑剂复合物通过改变核小体位置和翻译后修饰来调控基因转录，DNA复制和DNA修复。染色质重塑剂复合物分为四个家族：SWI / SNF，INO80 / SWR1，ISWI和CHD家族。在这篇综述中，我们描述了这些染色质重塑剂复合物的亚基，特别是ISWI家族的新成员和CHD家族的新颖性。长的非编码（lnc）RNA通过不同的表观遗传机制（包括与染色质重塑剂的相互作用）调节基因表达。例如，lncBRM与BRM的相互作用抑制了与分化表型相关的SWI / SNF复合物，并有利于干细胞相关的SWI / SNF复合物的组装。今天，