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Insult to Injury-Potential Contribution of Coronavirus Disease-19 to Neuroinflammation and the Development of HIV-Associated Neurocognitive Disorders
AIDS Research and Human Retroviruses ( IF 1.5 ) Pub Date : 2021-07-22 , DOI: 10.1089/aid.2020.0136
Monray Edward Williams 1 , Burtram Clinton Fielding 2
Affiliation  

Severe acute respiratory syndrome (SARS)-coronavirus (CoV)-2 is responsible for a new coronavirus disease known as coronavirus disease-19 (COVID-19). SARS-CoV-2 reports neurotropic properties and may have neurological implications, and this creates another health burden for people living with HIV. As yet, the impact of COVID-19 on (neuro)inflammation and the development of HIV-associated neurocognitive disorders (HAND) is not fully known. Here, we reviewed preliminary evidence that provides clues that COVID-19 may exacerbate inflammatory mechanisms related to the development of HAND.

中文翻译:

损害-冠状病毒病-19 对神经炎症和 HIV 相关神经认知障碍的发展的潜在贡献

严重急性呼吸系统综合症 (SARS)-冠状病毒 (CoV)-2 是导致一种称为冠状病毒病-19 (COVID-19) 的新型冠状病毒疾病的原因。SARS-CoV-2 具有嗜神经特性,可能具有神经学影响,这给 HIV 感染者带来了另一个健康负担。迄今为止,COVID-19 对(神经)炎症和 HIV 相关神经认知障碍 (HAND) 发展的影响尚不完全清楚。在这里,我们回顾了初步证据,这些证据提供了 COVID-19 可能加剧与 HAND 发展相关的炎症机制的线索。
更新日期:2021-07-24
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