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Acute and late neurological complications of COVID19: the quest for evidence
Brain ( IF 14.5 ) Pub Date : 2020-09-30 , DOI: 10.1093/brain/awaa294
Weixi Xiong 1, 2, 3 , Patrick Kwan 4, 5 , Dong Zhou 1 , Alessandra Del Felice 6 , John S Duncan 2, 3 , Josemir W Sander 2, 3, 7
Affiliation  

There is inevitable uncertainty when a new disease strikes and understanding the full spectrum of COVID-19 neurological complications is no exception. Neurologists in endemic areas are diligently working to understand the impact of COVID-19 on the nervous system. To date, more than 100 articles have been published on the neurological aspects of COVID-19 but there are insufficient high-quality cohort studies or case series to elucidate the full picture. We, therefore, read with interest, in Brain, the case series of potential acute neurological complications of COVID-19 in individuals seen at a tertiary neurological referral centre in the UK during the peak of the recent outbreak (Paterson et al., 2020). Forty-three clinical cases were described in detail including history, examination and extensive investigations. The authors are to be commended for their care and diligence. This case series adds to our knowledge about the potential spectrum of neurological features but, as noted by the authors, leaves many questions unanswered. Table 1 lists selected reports of neurological interest and complications.

中文翻译:

COVID19 的急性和晚期神经系统并发症:寻找证据

当一种新疾病来袭时,不可避免地存在不确定性,了解 COVID-19 神经系统并发症的全谱也不例外。流行地区的神经科医生正在努力了解 COVID-19 对神经系统的影响。迄今为止,已经发表了 100 多篇关于 COVID-19 神经学方面的文章,但没有足够的高质量队列研究或病例系列来阐明全貌。因此,我们饶有兴趣地阅读了《Brain》中近期爆发高峰期间在英国三级神经转诊中心就诊的个体中潜在的 COVID-19 急性神经并发症的病例系列(Paterson,2020) 。详细描述了四十三个临床病例,包括病史、检查和广泛调查。作者的细心和勤奋值得赞扬。这个病例系列增加了我们对神经学特征的潜在范围的了解,但正如作者指出的,仍有许多问题没有得到解答。表 1 列出了神经学兴趣和并发症的精选报告。
更新日期:2020-09-30
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