The discovery of sequence motifs mediating DNA-protein binding usually implies the determination of binding sites using high-throughput sequencing and peak calling. The determination of peaks, however, depends strongly on data quality and is susceptible to noise.

中文翻译：

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NoPeak：在ChIP-Seq数据中基于k-mer的基序发现而无需峰调用

介导DNA-蛋白质结合的序列基序的发现通常意味着使用高通量测序和峰调用来确定结合位点。但是，峰值的确定很大程度上取决于数据质量，并且容易受到噪声的影响。