Abstract

Four p-coumaroylated sesquiterpenoids (1–4), including three new ones (1, 2, and 4), were isolated from the whole plants of Pilea cavaleriei. Their structures were established on the basis of comprehensive spectroscopic analysis and comparison with data reported in the literature. Compounds 1–4 were evaluated for their antimycobacterial activities, and 2 and 4 were active against Mycobacterium tuberculosis H₃₇Rv with the MIC values of 19.6 ± 0.19 and 17.4 ± 0.12 μg/mL, respectively.

中文翻译：

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来自 Pilea cavaleriei 的三种新的 p-香豆酰化倍半萜

摘要

从Pilea cavaleriei的全株中分离出四种对香豆酰化倍半萜类化合物（1-4），其中包括三种新化合物（1、2和4 ） 。它们的结构是在综合光谱分析和与文献报道的数据比较的基础上建立的。评估了化合物1-4的抗分枝杆菌活性，化合物2和4对结核分枝杆菌H ₃₇ Rv 具有活性，MIC 值分别为 19.6 ± 0.19 和 17.4 ± 0.12 μg/mL。