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Mesenchymal stem cells prevent overwhelming inflammation and reduce infection severity via recruiting CXCR3+ regulatory T cells
Clinical & Translational Immunology ( IF 5.8 ) Pub Date : 2020-09-30 , DOI: 10.1002/cti2.1181
Wenchao Li 1 , Weiwei Chen 1 , Saisai Huang 1 , Genhong Yao 1 , Xiaojun Tang 1 , Lingyun Sun 1
Affiliation  

Mesenchymal stem cells (MSCs) have shown great potential in treating autoimmune diseases (ADs). Unlike the traditional immunosuppressants, which inadvertently impair patients' antimicrobial immunity, MSCs reduce the incidence and duration of respiratory infection. However, the underlying mechanisms are unknown.

中文翻译:

间充质干细胞通过募集 CXCR3+ 调节性 T 细胞来预防过度炎症并降低感染严重程度

间充质干细胞 (MSCs) 在治疗自身免疫性疾病 (ADs) 方面显示出巨大潜力。与会无意中损害患者抗菌免疫的传统免疫抑制剂不同,间充质干细胞可降低呼吸道感染的发生率和持续时间。然而,潜在的机制是未知的。
更新日期:2020-09-30
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