Late Mesozoic magmatism in southeastern China has been widely considered to be related to the subduction of the Paleo-Pacific Plate. However, it remains controversial whether mafic rocks are derived from the lithosphere or the asthenosphere. Here we present a comprehensive study on mafic dikes from Fujian Province in southeastern China, aiming to understand their source. Two types of mafic rocks have been recognized based on their trace-element features. Type-I rocks show arc-like trace-elemental characteristics, while type-II rocks are distinguished by their relatively flat patterns in primitive-mantle-normalized trace-element diagram. Despite such differences between two types of rocks, these mafic dikes show two trends in the plots of ⁸⁷Sr/⁸⁶Sr_(i) versus La/Nb, which can be explained by the influences of crustal contamination and melt-lithospheric mantle interaction, respectively. ⁸⁷Sr/⁸⁶Sr(i), La/Nb, Sr/Y and Zr/Y ratios of type-I rocks are significantly correlated to the thickness of the underlying lithosphere, and the signals of lithosphere are clearer with increasing lithospheric thickness. This highlights the important influences of melt-lithosphere interaction during their formation. Such observations also indicate that these mafic rocks are more likely to have been originated from the asthenosphere rather than the lithospheric mantle.