As the worldwide use of assisted reproductive technologies (ART) continues to grow, there is a critical need to assess the safety of these treatment parameters and the potential adverse health effects of their use in adults and their offspring. While key elements remain similar across nations, geographic variations both in treatments and populations make generalizability challenging. We describe and compare the demographic factors between the USA and the UK related to ART use and discuss implications for research. The USA and the UK share some common elements of ART practice and in how data are collected regarding long-term outcomes. However, the monitoring of ART in these two countries each brings strengths that complement each other’s limitations.

随着辅助生殖技术（ART）在全球范围内的使用不断增长，迫切需要评估这些治疗参数的安全性以及它们对成人及其后代的潜在不良健康影响。虽然各国之间的关键要素仍然相似，但治疗方法和人群的地理差异使得普遍性具有挑战性。我们描述和比较美国和英国之间与 ART 使用相关的人口因素，并讨论对研究的影响。美国和英国在 ART 实践以及如何收集有关长期结果的数据方面具有一些共同点。然而，这两个国家对抗逆转录病毒疗法的监测各有优势，可以弥补彼此的局限性。