The use of natural compounds in medicine for the treatment of diseases started since ancient days. Though many natural compounds exhibit potent pharmacological activity, their medicinal application is limited by low solubility, permeability or stability. Therefore, pharmaceutical scientists are developing drug delivery systems and carriers that allow better efficacy and clinical success. For instance, nanocarriers, owing to their small size and unique surface properties, allow successful delivery of various drugs by modifying solubility, permeability and pharmacokinetics. Nanocarriers preserve encapsulated molecules from degradation and, in turn, enhance stability. Here, we review nanocarriers with focus on natural molecules including thymoquinone, resveratrol, artemisinin, silymarin, natural antibiotics and natural extracts, which are used in different disease conditions, for example Alzheimer’s, diabetes, microbial infections, inflammation and psoriasis.

自古以来，就开始在医学中使用天然化合物治疗疾病。尽管许多天然化合物显示出强效的药理活性，但其药物应用受到低溶解度，渗透性或稳定性的限制。因此，药物科学家正在开发药物递送系统和载体，以实现更好的疗效和临床成功。例如，由于纳米载体的小尺寸和独特的表面特性，它们可以通过改变溶解度，渗透性和药代动力学来成功递送各种药物。纳米载体可保护被包封的分子免于降解，进而提高稳定性。在这里，我们将重点研究天然载体上的纳米载体，包括胸腺醌，白藜芦醇，青蒿素，水飞蓟素，天然抗生素和天然提取物，