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Fabrication, characterization, and in vivo biocompatibility evaluation of titanium-niobium implants
Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine ( IF 1.8 ) Pub Date : 2020-09-28 , DOI: 10.1177/0954411920960854
Abdurrahman Yolun 1 , Murat Şimşek 2 , Mehmet Kaya 3 , Ebru Elibol Annaç 4 , Mustafa Köm 5 , Ömer Çakmak 6
Affiliation  

In this study, biocompatible titanium-niobium (Ti-Nb) alloys were fabricated by using powder metallurgy methods. Physical, morphological, thermal, and mechanical analyses were performed and their in vivo compatibility was evaluated. Besides α, β, and α″ martensitic phases, α+β Widmanstätten phase due to increasing sintering temperature was seen in the microstructure of the alloys. Phase transformation temperatures of the samples decreased as Nb content increased. The ratio of Nb in the samples affected their mechanical properties. No toxic effect was observed on implanted sites. This study shows that Ti-Nb alloys can be potentially used for orthopedic applications without any toxic effects.



中文翻译:

钛铌植入物的制备、表征和体内生物相容性评价

在这项研究中,生物相容性钛铌 (Ti-Nb) 合金是通过使用粉末冶金方法制造的。进行了物理、形态、热和机械分析,并评估了它们的体内相容性。除了 α、β 和 α" 马氏体相,在合金的显微组织中还可以看到由于烧结温度升高而产生的 α+β Widmanstätten 相。样品的相变温度随着 Nb 含量的增加而降低。样品中 Nb 的比例影响了它们的机械性能。在植入部位未观察到毒性作用。该研究表明,Ti-Nb 合金可潜在地用于矫形应用而没有任何毒性作用。

更新日期:2020-09-29
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