MIC and minimum biofilm bactericidal concentration (MBBC) values of eravacycline against 185 staphylococci from periprosthetic joint infections were determined. Staphylococcus aureus had MICs of ≤0.25 μg/ml. MICs for methicillin-susceptible and -resistant Staphylococcus epidermidis were ≤1 and ≤2 μg/ml, respectively. S. aureus and S. epidermidis MBBC₅₀ and MBBC₉₀ values were 8 and 16 μg/ml for each, showing poor anti-staphylococcal biofilm activity using the method studied.

中文翻译：

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Eravacycline对从假肢周围感染中分离的葡萄球菌的浮游生物和生物膜活性。

确定了来自假体周围关节感染的伊拉环素对185种葡萄球菌的MIC和最低生物膜杀菌浓度（MBBC）值。金黄色葡萄球菌的MIC≤0.25μg/ ml。对甲氧西林敏感和耐药的表皮葡萄球菌的MIC分别为≤1和≤2μg/ ml。金黄色葡萄球菌和表皮葡萄球菌的MBBC ₅₀和MBBC ₉₀值分别为8和16μg/ ml，使用所研究的方法显示出较差的抗葡萄球菌生物膜活性。