Elucidation of the process of sex chromosome differentiation is necessary to understand the dynamics of evolutionary mechanisms in organisms. The W sex chromosome of the Siamese cobra (Naja kaouthia) contains a large number of repeats and shares amniote sex chromosomal linkages. Diversity Arrays Technology provides an effective approach to identify sex-specific loci that are epoch-making, to understand the dynamics of molecular transitions between the Z and W sex chromosomes in a snake lineage. From a total of 543 sex-specific loci, 90 showed partial homology with sex chromosomes of several amniotes and 89 loci were homologous to transposable elements. Two loci were confirmed as W-specific nucleotides after PCR amplification. These loci might result from a sex chromosome differentiation process and involve putative sex-determination regions in the Siamese cobra. Sex-specific loci shared linkage homologies among amniote sex chromosomes, supporting an ancestral super-sex chromosome.

阐明性染色体分化过程对于理解生物体进化机制的动力学是必要的。暹罗眼镜蛇 ( Naja kaouthia ) 的 W 性染色体) 包含大量重复并共享羊膜性染色体连锁。Diversity Arrays Technology 提供了一种有效的方法来识别具有划时代意义的性别特异性基因座，以了解蛇谱系中 Z 和 W 性染色体之间分子转换的动态。从总共 543 个性别特异性基因座中，90 个与几种羊膜动物的性染色体显示部分同源性，89 个基因座与转座因子同源。在 PCR 扩增后，两个基因座被确认为 W 特异性核苷酸。这些基因座可能来自性染色体分化过程，并涉及暹罗眼镜蛇中假定的性别决定区域。性别特异性基因座在羊膜动物性染色体之间共享连锁同源性，支持祖先的超性染色体。