In this work, solubility of exo-3,6-epoxy-1,2,3,6-tetrahydrophthalic anhydride (ETA) was measured and discussed in acetone + ethanol, methyl acetate + ethanol, 1,4-dioxane + ethanol, and ethyl acetate + ethanol mixture solvents in a temperature range from 278.15 to 323.15 K by a gravimetric method under 0.1 MPa. Experimental results indicated that solubility increased with temperature increasing and declined with the mass fraction increasing of ethanol in four kinds of mixture solvents. The solvent effect and Hansen solubility parameter were adopted to discuss the solubility behavior of ETA in selected solvents. Modeling correlation solubility data about ETA indicated that the Jouyban–Acree–Apelblat model (J–A–A) was more suitable than the Jouyban–Acree–Van’t Hoff model (J–A–V) and Ma and Sun model in mixture solvents. Processing of the dilution crystallization in acetone + ethanol system was chosen to separate and purify ETA on the basis of the solubility and solvent characteristics.

中文翻译：

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278.15至323.15 K混合溶剂中exo -3,6-环氧-1,2,3,6-四氢邻苯二甲酸酐的溶解度测定和模型分析

在这项工作中，exo的溶解度-3,6-环氧-1,2,3,6-四氢邻苯二甲酸酐（ETA）在丙酮+乙醇，乙酸甲酯+乙醇，1,4-二恶烷+乙醇和乙酸乙酯+乙醇混合溶剂中进行测量和讨论重量法在0.1 MPa下的温度范围为278.15至323.15K。实验结果表明，四种混合溶剂中，乙醇的溶解度均随温度的升高而增加，随乙醇质量分数的增加而降低。采用溶剂效应和Hansen溶解度参数讨论了ETA在所选溶剂中的溶解行为。关于ETA的相关溶解度数据建模表明，Jouyban–Acree–Apelblat模型（J–A–A）比Jouyban–Acree–Van't Hoff模型（J–A–V）和Ma and Sun模型更适合溶剂。