Bipolar I disorder (BD-I) is associated with a high risk of suicide attempt; however, the neural circuit dysfunction that confers suicidal vulnerability in individuals with this disorder remains largely unknown. Resting-state functional magnetic resonance imaging (rs-fMRI) allows non-invasive mapping of brain functional connectivity. The current study used an unbiased voxel-based graph theory analysis of rs-fMRI to investigate the intrinsic brain networks of BD-I patients with and without suicide attempt.

中文翻译：

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有自杀企图的双相 I 型障碍患者静息状态全局脑连接的改变

双相 I 型障碍 (BD-I) 与自杀企图的高风险相关；然而，导致患有这种疾病的个体容易自杀的神经回路功能障碍在很大程度上仍然未知。静息状态功能磁共振成像 (rs-fMRI) 允许对大脑功能连接进行非侵入性映射。目前的研究使用基于无偏体素的 rs-fMRI 图论分析来研究有和没有自杀企图的 BD-I 患者的内在大脑网络。