Intermolecular cross‐linking is a foundational technique in polymer science. The formation of covalent bond linkages between polymer chains creates multidimensional polymer architectures with desirable properties at the molecular, nano‐, micro‐ and macroscales. In their review article, Maddock et al., summarise recent progress in the development of biocatalytic methods for polymer cross‐linking, with a specific focus on the most promising candidate enzyme classes and their underlying catalytic mechanisms. The authors also describe exemplars of the use of enzyme catalysed cross‐linking reactions in industrially relevant applications, noting the limitations of these approaches and outlining strategies to mitigate reported deficiencies. (DOI: 10.1002/bip.23390)

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分子间交联是高分子科学中的基础技术。聚合物链之间共价键连接的形成创造了多维聚合物结构，在分子，纳米，微米和宏观尺度上都具有理想的性能。Maddock等人在其综述文章中总结了聚合物交联生物催化方法开发的最新进展，重点关注最有前途的候选酶类别及其潜在的催化机理。作者还描述了在工业相关应用中使用酶催化交联反应的示例，指出了这些方法的局限性，并概述了缓解已报告缺陷的策略。（DOI：10.1002 / bip.23390）