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Early resynchronization protocols for goats: Progestogens can be used prior to an early pregnancy diagnosis without affecting corpus luteum functionality
Reproduction in Domestic Animals ( IF 1.7 ) Pub Date : 2020-09-25 , DOI: 10.1111/rda.13830
Isabel Oliveira Cosentino 1 , Mario Felipe Alvarez Balaro 1 , Felipe Seabra Cardoso Leal 1 , Lucas de Figueiredo Cardoso Barbosa 1 , Fernanda Martins Gonçalves 1 , Gabriel Feliciano Felizardo 1 , Marina Monteiro Netto 1 , Felipe Zandonadi Brandão 1
Affiliation  

This study aimed to evaluate the exogenous progesterone (P4) effect on the luteal function from Day 16 to Day 21 of the oestrous cycle in inseminated goats with unknown pregnancy status. A total of 54 does passed through a short progestin‐based synchronization protocol and, on Day 16 of the following oestrous cycle, 27 does received a new P4 device which was retained until Day 21. Blood samples were collected daily from all does during this period, as well as on Day 24. Pregnancy diagnoses were performed on Day 30. Serum P4 values from 26 animals (GNPSP: Group of non‐pregnant does with second sponge: n = 8; GNPNSP: Group of non‐pregnant does without second sponge: n = 6; GPSP: Group of pregnant does with second sponge: n = 5; GPNSP: Group of pregnant does without second sponge: n = 7) were determined by radioimmunoassay commercial kits. No P4 differences were found between groups (GNPSP: 3.1 ± 2.8; 1.7 ± 1.8; 0.4 ± 1.0; and 0.0 ± 0.0 vs. GNPNSP: 4.4 ± 1.8; 3.0 ± 2.2; 0.8 ± 0.8; and 0.0 ± 0.0 or GPSP: 4.2 ± 1.0; 3.4 ± 0.6; 3.3 ± 1.6; 3.2 ± 0.9; 3.6 ± 1.2; 3.5 ± 1.3; 2.7 ± 1.3 vs. GPNSP: 4.4 ± 1.6; 3.6 ± 1.5; 3.7 ± 1.5; 3.8 ± 1.4; 3.2 ± 1.2; 3.1 ± 1.2; 3.6 ± 1.1; D16, D17, D18, D19, D20, D21, D24, respectively) or for the interaction of group and time. In conclusion, a second progestogen device had no effect on luteolysis or early pregnancy in the following oestrous cycle.

中文翻译:

山羊的早期重新同步方案:可以在早期妊娠诊断之前使用孕激素,而不会影响黄体功能

本研究旨在评估妊娠状态未知的受精山羊从发情周期的第16天到第21天,外源孕酮(P4)对黄体功能的影响。通过简短的基于孕激素的同步方案总共进行了54次检查,并且在下一个发情周期的第16天,有27位接受了新的P4设备,该设备一直保留到第21天。在此期间,每天从所有血液中采集血液样本,以及在第24天。在第30天进行了妊娠诊断。26只动物的血清P4值(G NPSP:非妊娠组加第二只海绵:n  = 8; G NPNSP:非妊娠组不加第二海​​绵第二海绵:n  = 6; G PSP:怀孕组用第二只海绵擦拭:n  = 5;G PNSP:没有第二块海绵的怀孕孕妇组:n  = 7)由放射免疫测定商业试剂盒测定。组间未发现P4差异(G NPSP:3.1±2.8; 1.7±1.8; 0.4±1.0;和0.0±0.0 vs.G NPNSP:4.4±1.8; 3.0±2.2; 0.8±0.8;和0.0±0.0或G PSP:4.2±1.0; 3.4±0.6; 3.3±1.6; 3.2±0.9; 3.6±1.2; 3.5±1.3; 2.7±1.3 vs.G PNSP:4.4±1.6; 3.6±1.5; 3.7±1.5;3.8±1.4;3.2±1.2; 3.1±1.2; 3.6±1.1; D16,D17,D18,D19,D20,D21,D24)或用于组和时间的交互。总之,第二个孕激素装置在接下来的发情周期中对黄体溶解或早期妊娠没有影响。
更新日期:2020-11-22
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