This study comprehensively investigated the impact of indoor carbon dioxide (CO₂) concentration on sleep quality. Three experimental conditions (800, 1900, 3000 ppm) were created in chambers decorated as bedroom and other environmental parameters that may influence the sleep quality were under strict control. Sleep quality of 12 subjects (6 men and 6 women) was monitored for 54 consecutive days through sleep quality questionnaire and physiological measures. Both subjective and physiological results showed that sleep quality decreased significantly with the increase of CO₂ concentration, and the comprehensive questionnaire score at 3000 ppm was only 80.8% of that at 800 ppm. A linear positive correlation was found between sleep onset latency (SOL) and CO₂ concentration, while a linear negative correlation occurred between slow‐wave sleep (SWS) and CO₂ concentration. In addition, in the same sleep environment, men had higher subjective questionnaire scores after wake‐up, longer SWS and shorter SOL, which lead to a better sleep quality compared with women, and there was a significant gender difference in sleep quality at 800 ppm (P < .05).

中文翻译：

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二氧化碳浓度影响睡眠质量的实验研究

本研究全面调查了室内二氧化碳 (CO ₂ ) 浓度对睡眠质量的影响。在装饰为卧室的房间中创建了三个实验条件（800、1900、3000 ppm），并严格控制其他可能影响睡眠质量的环境参数。通过睡眠质量问卷和生理指标连续54天监测12名受试者（6男6女）的睡眠质量。主观和生理结果均表明，随着CO ₂浓度的增加，睡眠质量显着下降，3000 ppm 时的综合问卷得分仅为800 ppm 时的80.8%。入睡潜伏期 (SOL) 与 CO ₂呈线性正相关浓度，而慢波睡眠 (SWS) 与 CO ₂浓度呈线性负相关。此外，在相同睡眠环境下，男性醒来后主观问卷得分更高，SWS更长，SOL更短，导致睡眠质量优于女性，800 ppm睡眠质量存在显着性别差异( P  < .05)。