Women and men exhibit differences in behavior when making value-based decisions. Various hypotheses have been proposed to explain these findings, stressing differences in functional lateralization of the brain, functional activation, neurotransmitter involvement and more recently, sex hormones. While a significant interaction of neurotransmitter systems and sex hormones has been shown for both sexes, decision-making in women might be particularly affected by variations of ovarian hormones. In this review we have gathered information from animal and human studies on how ovarian hormones affect decision-making processes in females by interacting with neurotransmitter systems at functionally relevant brain locations and thus modify the computation of decision aspects. We also review previous findings on impaired decision-making in animals and clinical populations with substance use disorder and depression, emphasizing how little we know about the role of ovarian hormones in aberrant decision-making.

中文翻译：

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卵巢激素对基于价值的决策系统的影响：对精神障碍性别二态性的影响

女性和男性在做出基于价值的决策时表现出不同的行为。已经提出了各种假设来解释这些发现，强调大脑功能侧化、功能激活、神经递质参与以及最近的性激素方面的差异。虽然神经递质系统和性激素之间存在显着的相互作用，但女性的决策可能特别受卵巢激素变化的影响。在这篇综述中，我们从动物和人类研究中收集了关于卵巢激素如何通过与功能相关的大脑位置的神经递质系统相互作用来影响女性决策过程的信息，从而修改决策方面的计算。