The presence of a complex of lipoprotein(a) and proprotein convertase subtilisin/kexin type 9 (PCSK9) in the blood of healthy volunteers and patients with cardiovascular diseases was analyzed by ELISA. The levels of the complex varied in a wide range and did not depend on the concentrations of Lp(a) and PCSK9. Moreover, the complex was found not only in patients with cardiovascular diseases, but also in healthy volunteers, which can indicate physiological role of lipoprotein(a) as PCSK9 transporter.

中文翻译：

---

ELISA测定血清中脂蛋白(a)和前蛋白转化酶枯草杆菌蛋白酶/可欣9型循环复合物

通过 ELISA 分析了健康志愿者和心血管疾病患者血液中脂蛋白 (a) 和前蛋白转化酶枯草杆菌蛋白酶 / kexin 9 型 (PCSK9) 复合物的存在。复合物的水平在很大范围内变化，不依赖于 Lp(a) 和 PCSK9 的浓度。此外，该复合物不仅在心血管疾病患者中发现，而且在健康志愿者中也发现，这可以表明脂蛋白 (a) 作为 PCSK9 转运蛋白的生理作用。