Background:Duplex ultrasound scanning (DUS) plays a major role in less invasive diagnosis and assessment of lesion severity in lower extremity peripheral artery disease (PAD). In this study, we evaluated the efficacy of each DUS parameter measured in patients with PAD and established a simple method for PAD evaluation.

Methods and Results:We retrospectively investigated 211 patients (270 limbs) who underwent assessment with both angiography and DUS. During DUS of the common femoral artery (CFA) and popliteal artery, we measured 3 parameters: acceleration time (AcT), peak systolic velocity (PSV), and waveform contour. We compared these parameters with the degree of angiographic stenosis. AcT at the CFA had a significantly higher value in prediction of aortoiliac artery lesions with >50% stenosis (c-index, 0.85; 95% confidence interval (CI), 0.79–0.91), with a sensitivity of 0.82 and specificity of 0.76 at the best cutoff point, compared with PSV and waveform contour (P<0.001, respectively). For femoropopliteal lesions, the ratio of AcT at the popliteal artery to AcT at the CFA is the most predictive parameter, with sensitivity of 0.86 and specificity of 0.92 at the best cutoff point (c-index, 0.93; 95% CI, 0.90–0.97), compared with others (P<0.001, respectively).

Conclusions:For the assessment of PAD with DUS, AcT and AcT ratio are simple and reliable parameters for evaluating aortoiliac and femoropopliteal artery disease.

背景：双面超声扫描（DUS）在低侵入性诊断和评估下肢周围动脉疾病（PAD）的病变严重程度中起主要作用。在这项研究中，我们评估了在PAD患者中测量的每个DUS参数的功效，并建立了一种简单的PAD评估方法。

方法和结果：我们回顾性研究了接受血管造影和DUS评估的211例患者（270肢）。在股总动脉（CFA）和pop动脉的DUS期间，我们测量了3个参数：加速时间（AcT），峰值收缩速度（PSV）和波形轮廓。我们将这些参数与血管造影狭窄程度进行了比较。CFA处的AcT在狭窄> 50％的主动脉ilia动脉病变的预测中具有较高的价值（c指数，0.85； 95％置信区间（CI），0.79–0.91），敏感性为0.82，0.76时特异性为0.76与PSV和波形轮廓相比，最佳截止点（分别为P <0.001）。对于股pop病变，the动脉的AcT与CFA的AcT之比是最可预测的参数，敏感性为0.86，特异性为0。

结论：用DUS评估PAD时，AcT和AcT比是评估主动脉和股pop动脉疾病的简单可靠的参数。