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Protective responses of antioxidant enzymes against bisphenol-A induced oxidative stress in Asian Seabass Lates calcarifer
Indian Journal of Geo-Marine Sciences ( IF 0.5 ) Pub Date : 2020-09-25
P Revathi, P Iyapparaj, R A Vasanthi, P Srinivasan, N Munuswamy, A Palavesam

Bisphenol A (BPA) is an endocrine disruptor used as plastic monomer and plasticizer widely present in the aquatic environment. In the present study, the effect of BPA on the antioxidant system in Lates calcarifer was documented. Three different concentrations such as 1, 10, 100 µg/l were selected and exposed to fishes for 30 days. After BPA exposure, antioxidant parameters were estimated against control. The levels of marker enzymes were assessed in the gill, muscle, liver and brain tissues. The results showed that the activities of superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx) and lipid peroxidation (LPx) were increased in treated groups than control. On the other hand, reduced glutathione (GSH) level was decreased in BPA exposed groups compared to control. Based on the results, imbalance in the antioxidant defence system clearly indicated that the BPA toxicity could lead to susceptible oxidative stress in various tissues of the fish L. calcarifer.

中文翻译:

抗氧化酶对亚洲雪鲈晚生鳞翅目双酚A诱导的氧化应激的保护反应。

双酚A(BPA)是一种内分泌干扰物,用作广泛存在于水生环境中的塑料单体和增塑剂。在本研究中,双酚A对晚钙生植物抗氧化系统的影响被记录下来。选择了三种不同的浓度,例如1、10、100 µg / l,并​​将其暴露在鱼类中30天。接触双酚A后,对照对照评估抗氧化剂参数。在the,肌肉,肝脏和脑组织中评估标记酶的水平。结果表明,与对照组相比,治疗组的超氧化物歧化酶(SOD),过氧化氢酶(CAT),谷胱甘肽过氧化物酶(GPx)和脂质过氧化物(LPx)的活性增加。另一方面,与对照组相比,BPA暴露组的谷胱甘肽(GSH)降低水平有所降低。根据结果​​,抗氧化防御系统的失衡清楚地表明,双酚A毒性可能导致鱼类L. calcarifer的各种组织中易感的氧化应激。
更新日期:2020-09-25
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