Abstract

Background:

Literature supports the use of serious games and virtual environments to assess cognitive functions and detect cognitive decline. This promising assessment method, however, has not yet been translated into self-administered screening instruments for pre-clinical dementia.

Objective:

The aim of this study is to assess the performance of a novel self-administered serious game-based test, namely the Virtual Supermarket Test (VST), in detecting mild cognitive impairment (MCI) in a sample of older adults with subjective memory complaints (SMC), in comparison with two well-established screening instruments, the Montreal Cognitive Assessment (MoCA) and the Mini-Mental State Examination (MMSE).

Methods:

Two groups, one of healthy older adults with SMC (N = 48) and one of MCI patients (N = 47) were recruited from day centers for cognitive disorders and administered the VST, the MoCA, the MMSE, and an extended pencil and paper neuropsychological test battery.

Results:

The VST displayed a correct classification rate (CCR) of 81.91% when differentiating between MCI patients and older adults with SMC, while the MoCA displayed of CCR of 72.04% and the MMSE displayed a CCR of 64.89%.

Conclusion:

The three instruments assessed in this study displayed significantly different performances in differentiating between healthy older adults with SMC and MCI patients. The VST displayed a good CCR, while the MoCA displayed an average CCR and the MMSE displayed a poor CCR. The VST appears to be a robust tool for detecting MCI in a population of older adults with SMC.

中文翻译：

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检测高危老年人群中的轻度认知障碍：一种新型的自我管理严重游戏筛查测试能否提高诊断准确性？

摘要

背景：

文献支持使用严肃游戏和虚拟环境来评估认知功能和检测认知能力下降。然而，这种有前途的评估方法尚未转化为自我管理的临床前痴呆症筛查工具。

客观的：

本研究的目的是评估一种新颖的自我管理的严肃游戏测试，即虚拟超市测试 (VST)，在检测具有主观记忆投诉的老年人样本中的轻度认知障碍 (MCI) 方面的表现。 SMC)，与两种成熟的筛查工具，蒙特利尔认知评估 (MoCA) 和简易精神状态检查 (MMSE) 进行比较。

方法：

两组，一组患有 SMC（N = 48）的健康老年人和一名 MCI 患者（N = 47）从认知障碍日间中心招募，并进行 VST、MoCA、MMSE 和延长的铅笔和纸神经心理学测试电池。

结果：

VST 在区分 MCI 患者和 SMC 老年人时显示正确分类率 (CCR) 为 81.91%，而 MoCA 显示 CCR 为 72.04%，MMSE 显示 CCR 为 64.89%。

结论：

本研究中评估的三种仪器在区分患有 SMC 和 MCI 患者的健康老年人方面表现出显着不同的性能。VST 显示出良好的 CCR，而 MoCA 显示出平均 CCR，而 MMSE 显示出较差的 CCR。VST 似乎是在患有 SMC 的老年人群中检测 MCI 的强大工具。