ABSTRACT

Fine and ultra-fine particulate matter (PM) are major constituents of urban air pollution and recognized risk factors for cardiovascular diseases. This review examined the effects of PM exposure on vascular tissue. Specific mechanisms by which PM affects the vasculature include inflammation, oxidative stress, actions on vascular tone and vasomotor responses, as well as atherosclerotic plaque formation. Further, there appears to be a greater PM exposure effect on susceptible individuals with pre-existing cardiovascular conditions.

中文翻译：

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环境颗粒物对血管组织的影响：综述

摘要

细颗粒物和超细颗粒物 (PM) 是城市空气污染的主要成分，也是公认的心血管疾病危险因素。该综述检查了 PM 暴露对血管组织的影响。PM 影响脉管系统的具体机制包括炎症、氧化应激、对血管张力和血管舒缩反应的作用，以及动脉粥样硬化斑块的形成。此外，PM 暴露对已有心血管疾病的易感个体的影响似乎更大。