A growing body of evidence pointed correlation between insulin‐resistance, testosterone level and infertility, but there is scarce information about mechanisms. The aim of this study was to identify the possible mechanism linking the insulin‐resistance with testosterone‐producing‐Leydig‐cells functionality.

中文翻译：

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由于女性化，小鼠 Leydig 细胞中胰岛素样生长因子信号传导的缺乏会增加睾酮向雌二醇的转化

越来越多的证据表明胰岛素抵抗、睾酮水平和不孕症之间存在相关性，但关于机制的信息很少。本研究的目的是确定将胰岛素抵抗与产生睾酮的 Leydig 细胞功能联系起来的可能机制。