The present work aims to prepare magnesium aluminate nanoparticles (MgAl₂O₄ NPs) using aluminum isopropoxide and magnesium ethoxide by hydrolysis reaction and to investigate them as new adsorbent materials for the extraction and clean-up of dimethomorph pesticide from tap water. The MgAl₂O₄ NPs were characterized by X-ray powder diffraction (XRD), Fourier-transform infrared spectroscopy (FTIR), field emission scanning electron microscopy (FESEM), and high-resolution transmission electron microscopy (HRTEM). The XRD result confirmed the formation of the spinal cubic structure in the fabricated sample. A solid-phase extraction (SPE) cartridge packed with MgAl₂O₄ NPs was used to extract dimethomorph pesticide from water samples. The extracted pesticide solution was quantified using a validated liquid chromatography mass spectrometry (LC-MS-MS) method. The limit of quantification (LOQ) was found to be 1$\mathrm{\mu }$g/L, signifying the sensitivity of the LC-MS-MS. The water samples were passed through the cartridges and investigated to find the adsorption strength of the pesticides under the influence of temperature, volume of sample, flow rate, pH and ionic strength on the efficiency of the cartridge. The extraction efficiency of the developed MgAl₂O₄ NPs SPE was found to be higher than that of commercially available SPE-$C_{18}$cartridge. The average recoveries of the pesticides ranged from 90%–94% which was obtained at two different fortification levels of 1 and 10 $\mathrm{\mu }$g/L using MgAl₂O₄ NPs SPE.

本工作旨在利用异丙醇铝和乙醇镁通过水解反应制备铝酸镁纳米颗粒（MgAl ₂ O ₄ NPs），并研究它们作为从自来水中提取和净化二甲基吗啡农药的新型吸附材料。通过X射线粉末衍射（XRD），傅立叶变换红外光谱（FTIR），场发射扫描电子显微镜（FESEM）和高分辨率透射电子显微镜（HRTEM）对MgAl ₂ O ₄ NP进行了表征。XRD结果证实了所制备样品中脊柱立方结构的形成。装有MgAl ₂ O _4的固相萃取（SPE）柱NP用于从水样中提取二甲基吗啡农药。使用经过验证的液相色谱质谱法（LC-MS-MS）对提取的农药溶液进行定量。发现定量限（LOQ）为1$\mathrm{\mu }$g / L，表示LC-MS-MS的灵敏度。将水样品通过小柱，并进行研究以求出在温度，样品量，流速，pH和离子强度对小柱效率的影响下农药的吸附强度。发现已开发的MgAl ₂ O ₄ NPs SPE的提取效率高于市售SPE-$C_{\mathrm{18岁}}$墨盒。农药的平均回收率在90％–94％范围内，这是在两种不同的设防水平1和10下获得的$\mathrm{\mu }$g / L使用MgAl ₂ O ₄ NPs SPE。