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Novel synthetic approach to pyrrolo[1,2- b ]cinnolines
Chemistry of Heterocyclic Compounds ( IF 1.5 ) Pub Date : 2020-09-25 , DOI: 10.1007/s10593-020-02770-w
Anastasia T. Plieva , Petrakis N. Chalikidi , Andrey V. Gutnov , Anatolij M. Turiev , Oleg P. Demidov , Nicolai A. Aksenov , Taimuraz T. Magkoev , Vladimir T. Abaev

Straightforward method for the synthesis of pyrrolo[1,2-b]cinnolines starting from 2-nitrobenzaldehydes and 2-methylfurans has been elaborated. The key steps of the process are oxidative furan ring opening with diazonium cation and intramolecular alkylation of azo group of the resulted cinnoline with secondary allyl alcohol.



中文翻译:

吡咯并[1,2-b] cinnolines的新型合成方法

提出了一种简单的方法,以2-硝基苯甲醛和2-甲基呋喃为原料合成吡咯并[1,2- b ] cinnolines。该方法的关键步骤是用重氮阳离子将呋喃氧化开环,并用仲烯丙醇将所得肉桂醇的偶氮基团进行分子内烷基化。

更新日期:2020-09-25
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