In the last decade, the scientific community has witnessed explosive growth in research on the direct carbamoylation of C–H and X–H (X = N, O) bonds with formamides via cross-dehydrogenative coupling reactions. This novel approach is an effective means of preparing a variety of carboxamide, carbamate as well as urea derivatives, which are prevalent in medicinal chemistry and natural product synthesis. This review elaborates the most important advances and developments in the field, with an emphasis on the reaction patterns and mechanisms.

中文翻译：

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甲酰胺基C（sp2）-H与XH（X = C，O，N）键之间的交叉脱氢偶联反应。

在过去的十年中，科学界见证了通过交叉脱氢偶联反应将CH和XH（X = N，O）与甲酰胺进行直接氨基甲酰化的研究呈爆炸性增长。这种新颖的方法是制备各种在医学化学和天然产物合成中普遍使用的羧酰胺，氨基甲酸酯以及尿素衍生物的有效手段。这篇综述阐述了该领域最重要的进展和发展，重点是反应模式和机理。