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Evaluation of hydroxyapatite- and zinc-coated Ti-6Al-4V surface for biomedical application using electrochemical process
Journal of the Australian Ceramic Society ( IF 1.9 ) Pub Date : 2020-09-24 , DOI: 10.1007/s41779-020-00517-6
Rakesh Kumar , R. Thanigaivelan , G. K. Rajanikant , T. Jagadeesha , Jyotirekha Das

In this research, the cell viability is tested on the surface-modified implants. Electrochemical setup is used for coating the hydroxyapatite (HA) powder and nano zinc particle (Zn)n on the Ti-6Al-4 V alloy. The electrolyte is prepared by mixing the HA and (Zn)n of varying quantity, and the effect of electrochemical parameter on surface coating thickness, surface quality and cell viability was studied. Based on the study, the cell viability is observed to be maximum at HA and (Zn)n concentration of 6 g/L and 0.8 g/L, respectively. The (Zn)n concentration in the range of 0.8 to 1.2 g/L and voltage of 12–13 V is suitable for obtaining the controlled coating thickness. During the electrochemical process, the nanopores HA structures with a pore size of 215–786 nm are obtained attributes for better cells attachment on the surface. The cell viability is found high (0.366) at 6 g/L HA and 1.6 g/L of (Zn)n concentration at 14 V.



中文翻译:

使用电化学方法评估生物医学应用的羟基磷灰石和锌涂层Ti-6Al-4V表面

在这项研究中,在表面修饰的植入物上测试了细胞活力。电化学设置用于在Ti-6Al-4 V合金上涂覆羟基磷灰石(HA)粉末和纳米锌颗粒(Zn)n。通过混合不同量的HA和(Zn)n制备电解质,并研究了电化学参数对表面涂层厚度,表面质量和电池活力的影响。根据这项研究,在HA和(Zn)n浓度分别为6 g / L和0.8 g / L时,观察到细胞活力最高。(锌)n浓度范围在0.8至1.2 g / L和12-13 V的电压适合于获得受控的涂层厚度。在电化学过程中,获得了孔径为215–786 nm的纳米孔HA结构,以使细胞更好地附着在表面上。发现在6 g / L HA时细胞活力很高(0.366),在14 V时浓度为1.6 g / L(Zn)n

更新日期:2020-09-25
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