Particle deposition during crossflow filtration is significantly influenced by the operating conditions, in particular the permeate flux and crossflow velocity. However, there is a lack of detailed knowledge about how deposit layer structures and distributions depend on operating parameters. This study uses a microfluidic visualisation filtration system to examine the influence of operating conditions on the deposition process during crossflow ultrafiltration from a microscopic perspective. Increasing the permeate flux caused an increasing amount of deposition and a thicker deposit layer. Higher crossflow velocities reduced the extent of deposition. The degree of deposition varied over a range of operating conditions due to the altered hydrodynamic forces exerted on the particles, which can be examined by the deposition probability according to an existing model. Building on this, an empirical correlation between the deposition probability and volume of deposition as a function of filtration time was developed, which gave good agreement with experimental results. The effect of solution conditions was also involved in this correlation as a interaction energies. This could be useful for predicting the dynamic deposition process during crossflow filtration over a range of operating and solution conditions.

错流过滤过程中的颗粒沉积受操作条件的影响很大，尤其是渗透通量和错流速度。但是，缺乏有关沉积层结构和分布如何取决于运行参数的详细知识。这项研究使用微流体可视化过滤系统从微观角度检查错流超滤过程中操作条件对沉积过程的影响。渗透通量的增加导致沉积量的增加和较厚的沉积层。较高的错流速度降低了沉积程度。由于作用在颗粒上的流体动力的变化，沉积程度在一定的操作条件范围内变化，可以根据现有模型通过沉积概率进行检查。在此基础上，建立了沉积概率与沉积量随过滤时间变化的经验关系，与实验结果吻合良好。溶液条件的影响也作为相互作用能参与了这种关系。这对于预测一定范围的操作和溶液条件下错流过滤过程中的动态沉积过程可能很有用。