Functional four-dimensional spectral–spatial electron paramagnetic imaging (EPRI) is routinely used in biomedical research. Positions and widths of EPR lines in the spectral dimension report oxygen partial pressure, pH, and other important parameters of the tissue microenvironment. Images are measured in the homogeneous external magnetic field. An application of EPRI is proposed in which the field is perturbed by a magnetized object. A proof-of-concept imaging experiment was conducted, which permitted visualization of the magnetic field created by this object. A single-line lithium octa-n-butoxynaphthalocyanine spin probe was used in the experiment. The spectral position of the EPR line directly measured the strength of the perturbation field with spatial resolution. A three-dimensional magnetic field map was reconstructed as a result. Several applications of this technology can be anticipated. First is EPRI/MPI co-registration, where MPI is an emerging magnetic particle imaging technique. Second, EPRI can be an alternative to magnetic field cameras that are used for the development of high-end permanent magnets and their assemblies, consumer electronics, and industrial sensors. Besides the high resolution of magnetic field readings, EPR probes can be placed in the internal areas of various assemblies that are not accessible by the standard sensors. Third, EPRI can be used to develop systems for magnetic manipulation of cell cultures.

中文翻译：

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快速扫描 EPR 成像作为磁场绘图工具

功能性四维光谱空间电子顺磁成像（EPRI）通常用于生物医学研究。EPR 线在光谱维度上的位置和宽度报告了氧分压、pH 值和组织微环境的其他重要参数。图像是在均匀的外部磁场中测量的。提出了 EPRI 的应用，其中磁场受到磁化物体的扰动。进行了概念验证成像实验，使该物体产生的磁场可视化。实验中使用单线锂八正丁氧基萘酞菁自旋探针。EPR线的光谱位置直接测量了具有空间分辨率的微扰场的强度。结果重建了三维磁场图。可以预见该技术的多种应用。首先是 EPRI/MPI 联合注册，其中 MPI 是一种新兴的磁粒子成像技术。其次，EPRI 可以替代磁场相机，用于开发高端永磁体及其组件、消费电子产品和工业传感器。除了高分辨率的磁场读数外，EPR 探头还可以放置在标准传感器无法访问的各种组件的内部区域。第三，EPRI 可用于开发细胞培养物磁力操纵系统。