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Anti-GPC3 Antibody-Conjugated BEZ235 Loaded Polymeric Nanoparticles (Ab-BEZ235-NP) Enhances Radiosensitivity in Hepatocellular Carcinoma Cells by Inhibition of DNA Double-Strand Break Repair.
Journal of Biomedical Nanotechnology ( IF 2.9 ) Pub Date : 2020-9-25 , DOI: 10.1166/jbn.2020.2834 Yong Liang , Chunmei Xie , Amin Li , Zhen Huo , Binquan Wu , Shiyu Cai , Weiya Cao , Yongfang Ma , Ruyue Xu , Zhenyou Jiang , Dong Ma , Xiaolong Tang
Journal of Biomedical Nanotechnology ( IF 2.9 ) Pub Date : 2020-9-25 , DOI: 10.1166/jbn.2020.2834 Yong Liang , Chunmei Xie , Amin Li , Zhen Huo , Binquan Wu , Shiyu Cai , Weiya Cao , Yongfang Ma , Ruyue Xu , Zhenyou Jiang , Dong Ma , Xiaolong Tang
To assess AB-BEZ235-NP potential as a radio-sensitizer in hepatocellular carcinoma models.
中文翻译：
抗GPC3抗体结合的BEZ235负载聚合物纳米颗粒（Ab-BEZ235-NP）通过抑制DNA双链断裂修复增强了肝癌细胞的放射敏感性。
评估AB-BEZ235-NP在肝细胞癌模型中作为放射增敏剂的潜力。
更新日期：2020-09-26
中文翻译：
抗GPC3抗体结合的BEZ235负载聚合物纳米颗粒（Ab-BEZ235-NP）通过抑制DNA双链断裂修复增强了肝癌细胞的放射敏感性。
评估AB-BEZ235-NP在肝细胞癌模型中作为放射增敏剂的潜力。
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