Cancer is the most devastating disease in the present scenario, killing millions of people every year. Early detection, accurate diagnosis, and timely treatment are considered to be the most effective ways to control this disease. Rapid and efficient detection of cancer at their earliest stage is one of the most significant challenges in cancer detection and cure. Numerous diagnostic modules have been developed to detect cancer cells early. As nucleic acid equivalent to antibodies, aptamers emerge as a new class of molecular probes that can identify cancer-related biomarkers or circulating rare cancer/ tumor cells with very high specificity and sensitivity. The amalgamation of aptamers with the biosensing platforms gave birth to "Aptasensors." The advent of highly sensitive aptasensors has opened up many new promising point-of-care diagnostics for cancer. This comprehensive review focuses on the newly developed aptasensors for cancer diagnostics.

癌症是目前情况下最具破坏性的疾病，每年造成数百万人死亡。早期发现、准确诊断、及时治疗被认为是控制本病最有效的方法。在早期阶段快速有效地检测癌症是癌症检测和治疗中最重大的挑战之一。已经开发了许多诊断模块来早期检测癌细胞。作为与抗体等价的核酸，适体作为一类新的分子探针出现，可以以非常高的特异性和灵敏度识别癌症相关的生物标志物或循环罕见的癌症/肿瘤细胞。适体与生物传感平台的融合催生了“适体传感器”。高灵敏度适体传感器的出现开辟了许多新的有前途的癌症即时诊断方法。这篇综合评论的重点是新开发的用于癌症诊断的适体传感器。