ABSTRACT Cognitive behavioural therapy (CBT) is an effective psychological treatment for anxiety-related disorders (anxiety disorders, post-traumatic stress disorder, and obsessive-compulsive disorder). However, relapse of anxiety symptoms is common following completion of treatment. This study aimed to identify predictors of relapse of anxiety after CBT for adult (18+) patients to enable the identification of “at-risk” patients who could potentially benefit from relapse prevention interventions. A systematic review and meta-analysis were conducted, including studies found in PsycINFO, PubMed, Scopus, and Web of Science, and through hand-searches of references lists and reverse citations. Nine studies met eligibility criteria (N = 532 patients). On average, 23.8% of patients experienced relapse following completion of CBT. A total of 21 predictors were identified and grouped into seven categories: residual symptoms; personality disorders; medication; clinical features; stressful life-events; degree of improvement; and demographics. A meta-analysis of residual symptoms as a predictor of relapse yielded a moderate but non-significant-pooled effect size (r = 0.35; 95% CI −0.21, 0.74, p =.08). Further research with adequately powered samples and standardised operationalisations of relapse are required to identify robust predictors.

中文翻译：

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焦虑相关障碍的认知行为治疗后复发和复发的预测因素：系统评价

摘要 认知行为疗法 (CBT) 是一种针对焦虑相关障碍（焦虑症、创伤后应激障碍和强迫症）的有效心理治疗方法。然而，在完成治疗后，焦虑症状的复发是常见的。本研究旨在确定成人（18 岁以上）患者 CBT 后焦虑复发的预测因素，以识别可能从预防复发干预措施中受益的“高危”患者。进行了系统回顾和荟萃分析，包括在 PsycINFO、PubMed、Scopus 和 Web of Science 中发现的研究，以及通过手动搜索参考文献列表和反向引用。九项研究符合资格标准（N = 532 名患者）。平均而言，23.8% 的患者在完成 CBT 后出现复发。总共确定了 21 个预测因子并将其分为七类：残留症状；人格障碍；药物; 临床表现; 压力大的生活事件；改善程度；和人口统计。残留症状作为复发预测因子的荟萃分析产生了中等但不显着的汇总效应大小（r = 0.35；95% CI -0.21, 0.74, p =.08）。需要对具有足够能力的样本和复发的标准化操作进行进一步研究，以确定可靠的预测因子。08）。需要对具有足够能力的样本和复发的标准化操作进行进一步研究，以确定可靠的预测因子。08）。需要对具有足够能力的样本和复发的标准化操作进行进一步研究，以确定可靠的预测因子。