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Combined Preparation of Human Olfactory Ensheathing Cells in the Therapy of Post-Traumatic Cysts of the Spinal Cord
Bulletin of Experimental Biology and Medicine ( IF 0.7 ) Pub Date : 2020-08-01 , DOI: 10.1007/s10517-020-04925-3
A D Voronova 1 , O V Stepanova 1, 2 , M P Valikhov 1, 2 , A V Chadin 1 , A S Semkina 1 , E K Karsuntseva 1, 3 , G A Fursa 1, 3 , I V Reshetov 4 , V P Chekhonin 1
Affiliation  

In experiments on rats, co-transplantation of olfactory ensheathing cells of the human olfactory mucosa and neural stem/progenitor cells from the same source into post-traumatic cysts of the spinal cord led to improvement of the motor activity of the hind limbs and reduced the size of the cysts in some animals by 4-12%. The transplantation of a combination of the olfactory mucosa cells is effective and can be used in preclinical trials for the treatment of spinal cord injuries.

中文翻译:

人嗅鞘细胞在脊髓创伤后囊肿治疗中的联合制备

在大鼠实验中,将人嗅粘膜的嗅鞘细胞和来自同一来源的神经干/祖细胞共同移植到脊髓的创伤后囊肿中,导致后肢运动活动得到改善,并减少了一些动物的包囊大小增加了 4-12%。嗅粘膜细胞组合的移植是有效的,可用于治疗脊髓损伤的临床前试验。
更新日期:2020-08-01
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