This pilot study investigates the correlation between psychological stress and antiretroviral therapy (ART) adherence and plasma HIV RNA (viral load) as mediated by psychological flexibility among Black men in the south. Data were collected from 48 HIV-positive, low income Black men. Results indicate a strong positive correlation between perceived stress and psychological inflexibility (adjusted for age and income r_s = 0.67; p < 0.001), a negative correlation between psychological inflexibility and ART adherence (adjusted r_s = − 0.32; p = 0.03), a negative correlation between perceived stress and ART adherence (adjusted r_s = − 0.45; p = 0.006), and a negative correlation between ART adherence and viral load (adjusted r_s = − 0.37; p = 0.04). Our findings suggest stress decreases adherence to ART and viral suppression among Black men living with HIV. However, psychological flexibility did not mediate the relationship between stress and treatment adherence. Hair cortisol concentrations were high (mean of 34.2 pg/mg), but uncorrelated with adherence.

这项初步研究调查了心理压力与抗逆转录病毒疗法 (ART) 依从性和血浆 HIV RNA（病毒载量）之间的相关性，这是由南方黑人男性的心理灵活性介导的。数据收集自 48 名 HIV 阳性的低收入黑人男性。结果表明，感知压力与心理不灵活之间存在很强的正相关（根据年龄和收入调整 rs ₌  0.67；p < 0.001），心理不灵活与 ART 依从性之间呈负相关（调整后 rs ₌  − 0.32；p = 0.03），感知压力与 ART 依从性之间呈负相关（调整后_的rs  = − 0.45；p = 0.006），ART 依从性和病毒载量之间呈负相关（调整后_的rs = - 0.37; p = 0.04）。我们的研究结果表明，压力会降低感染 HIV 的黑人男性对 ART 和病毒抑制的依从性。然而，心理灵活性并没有调节压力与治疗依从性之间的关系。头发皮质醇浓度很高（平均为 34.2 pg/mg），但与依从性无关。