Religion and spirituality have been associated with higher survival and improved biological markers among people living with HIV/AIDS (PLWH). Prior results have largely been among small cohort studies. We examined the association using a larger sample and longitudinal data from the Veterans Aging Cohort Study (VACS) years 2002–2012 (n = 3,685). Attending services at least monthly was associated with higher social support (80% vs 75%, p = 0.002), less unhealthy alcohol use (35% vs 39%, p = 0.006), less marijuana use in the past year (23% vs 32%, p < 0.001), less overall drug use within the past year (27% vs 31%, p = 0.01), and lower depression (20% vs 24%, p = 0.004). Attending services monthly was associated with a reduced mortality risk adjusting for age, race, gender, education, MSM, HCV, VL, CD4, and adherence to ARV (adjusted HazardRatio [aHR] = 0.89, 0.80–0.99). However, after controlling for smoking status, this association of mortality and religious attendance became non-significant (aHR = 0.93, 0.84–1.04).

宗教和灵性与 HIV/AIDS (PLWH) 感染者的更高生存率和生物标志物改善有关。先前的结果主要来自小型队列研究。我们使用来自退伍军人老龄化队列研究 (VACS) 年 2002-2012 (n = 3,685) 的更大样本和纵向数据检查了这种关联。至少每月参加一次服务与更高的社会支持（80% vs 75%，p = 0.002）、减少不健康饮酒（35% vs 39%，p = 0.006）、减少过去一年的大麻使用（23% vs 32%，p < 0.001），过去一年内总体药物使用量减少（27% 对 31%，p = 0.01），抑郁症降低（20% 对 24%，p = 0.004）。根据年龄、种族、性别、教育、MSM、HCV、VL、CD4、以及对 ARV 的依从性（调整后的 HazardRatio [aHR] = 0.89, 0.80–0.99）。然而，在控制吸烟状况后，这种死亡率和宗教信仰的关联变得不显着（aHR = 0.93, 0.84-1.04）。